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2020 – Gastroesophageal reflux disease (GERD)

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Title: Night sweats as a manifestation of gastroesophageal reflux disease
Authors: Alexei Berdnikov, Stacy McPhee, Lisa LaBine, Tunji Fatoye
Published: Can Fam Physician. 2020 Dec;66(12):901-903. doi: 10.46747/cfp.6612901.


Gastroesophageal reflux disease (GERD) is a common condition in which gastric contents flow retrograde past the lower esophageal sphincter causing irritation and damage to the esophagus. Common symptoms associated with this disease include heartburn, chest pain, vomiting, and a hoarse voice. In most cases, some permutation of these symptoms is enough to make the diagnosis, and resolution of symptoms with acid suppression therapy strengthens the diagnostic probability. Despite the unusual association between night sweats and GERD, this case report contributes to the literature underscoring the importance of considering GERD in the diagnostic workup for night sweats. Currently, there is very little evidence to support GERD as a cause of night sweats, with previous associations between GERD and night sweats based mostly on informal observations.

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